Search on: PROTEIN TYROSINE PHOSPHATASES 
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Descriptor English:   Protein Tyrosine Phosphatases 
Descriptor Spanish:   Proteínas Tirosina Fosfatasas 
Descriptor Portuguese:   Proteínas Tirosina Fosfatases 
Synonyms English:   PTPase
Phosphotyrosyl Protein Phosphatase
Protein-Tyrosine Phosphatase
Phosphatase, Phosphotyrosine
Phosphatase, Phosphotyrosyl Protein
Phosphatase, Protein-Tyrosine
Phosphatase, Tyrosyl Phosphoprotein
Phosphatases, Protein Tyrosine
Phosphoprotein Phosphatase, Tyrosyl
Protein Phosphatase, Phosphotyrosyl
Protein Tyrosine Phosphatase
Tyrosine Phosphatases, Protein
Phosphotyrosine Phosphatase
Protein-Tyrosine-Phosphatase
Tyrosyl Phosphoprotein Phosphatase  
Tree Number:   D08.811.277.352.650.775
Definition English:   An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis. 
Indexing Annotation English:   general; prefer specifics
History Note English:   2008(1985) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   29866 
Unique Identifier:   D017027 

Occurrence in VHL:
 

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